• Slow Taper off Antimalarial Is Best to Avoid Lupus Flare During Remission

  Slowly tapering off – or remaining on – antimalarial medications can help prevent disease flare in patients with systemic lupus erythematosus (SLE) who've achieved clinical remission for at least

  2020-11-30

• Prognostic impact of peripheral blood neutrophil to lymphocyte ratio in advanced-stage pulmonary large cell neuroendocrine carcinoma and its association with the immune-related tumour microenvironment

  AbstractBackgroundThe prognostic value of the neutrophil-to-lymphocyte ratio (NLR) with large cell neuroendocrine carcinoma (LCNEC) patients remains unclear. Thus, we performed a retrospective study t

  2020-11-30

• Blood Vessels in the Eye May Diagnose Parkinson's Disease

  An eye exam may be all that is needed to diagnose Parkinson's disease, new research shows.Maximillian DiazUsing an advanced machine-learning algorithm and fundus eye images, which depict the small

  2020-11-29

• Open resource of clinical data from patients with pneumonia for the prediction of COVID-19 outcomes via deep learning

  AbstractData from patients with coronavirus disease 2019 (COVID-19) are essential for guiding clinical decision making, for furthering the understanding of this viral disease, and for diagnostic model

  2020-11-08

• Measuring targeting specificity of genome-editing by nuclear transfer and sequencing (NT-seq)

  Dear Editor,Evaluation of targeting specificity of genome editing tools is of paramount significance. However, existing off-target detection methods only work under certain conditions, and different e

  2020-11-04

• Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro

  AbstractThe cell entry of SARS-CoV-2 has emerged as an attractive drug repurposing target for COVID-19. Here we combine genetics and chemical perturbation to demonstrate that ACE2-mediated entry of SA

  2020-11-04

• EMA Recommends First Long-Acting Injectable HIV Treatment

  The first long-acting injectable treatments for HIV were recommended for marketing approval on October 16 by the European Medicines Agency (EMA).A combination injection of two new antiretrov

  2020-10-19

• Social Factors Predicted Peripartum Depressive Symptoms in Black Women With HIV

  Black women living with HIV are a high-risk population for peripartum depressive symptoms, based on data from 143 women.Women with high-risk pregnancies because of chronic conditions are at increased

  2020-10-19